Exercise Causes Epigenetic Changes To Fat Cells

A Comprehensive Map of AncestryDNA Ethnicity Regions

Altered DNA methylation as a result of physical activity could be one of the mechanisms of how these genes affect the risk of disease.

 

Exercise, even in small doses, changes the expression of our innate DNA. New research from Lund University in Sweden has described for the first time what happens on an epigenetic level in fat cells when we undertake physical activity.

“Our study shows the positive effects of exercise, because the epigenetic pattern of genes that affect fat storage in the body changes”, says Charlotte Ling, Associate Professor at Lund University Diabetes Centre.

The cells of the body contain DNA, which contains genes. We inherit our genes and they cannot be changed. The genes, however, have ‘methyl groups’ attached which affect what is known as ‘gene expression’ – whether the genes are activated or deactivated. The methyl groups can be influenced in various ways, through exercise, diet and lifestyle, in a process known as ‘DNA methylation’. This is epigenetics, a relatively new research field that in recent years has attracted more and more attention.

In the study, the researchers investigated what happened to the methyl groups in the fat cells of 23 slightly overweight, healthy men aged around 35 who had not previously engaged in any physical activity, when they regularly attended spinning and aerobics classes over a six-month period.

“They were supposed to attend three sessions a week, but they went on average 1.8 times”, says Tina Rönn, Associate Researcher at Lund University.

Using technology that analyses 480,000 positions throughout the genome, they could see that epigenetic changes had taken place in 7,000 genes (an individual has 20–25 000 genes). They then went on to look specifically at the methylation in genes linked to type 2 diabetes and obesity.

“We found changes in those genes too, which suggests that altered DNA methylation as a result of physical activity could be one of the mechanisms of how these genes affect the risk of disease”, says Tina Rönn, adding that this has never before been studied in fat cells and that they now have a map of the DNA methylome in fat.

In the laboratory, the researchers were able to confirm the findings in vitro (studying cell cultures in test tubes) by deactivating certain genes and thus reducing their expression. This resulted in changes in fat storage in fat cells.

 

Food Pyramid Built On Shaky Ground

Tart Cherry Juice Lowers Blood Pressure
Tart Cherry Juice Lowers Blood Pressure

Recommendations Not Based On Clinical Data

The latest issue of Nutrition News contains an interview with Ann Louise Gittleman, the first lady of nutrition. She was the one calling a flag on the play back in the 80’s when we were being told that fat is dangerous. “Eat Fat, Lose Weight” breaks down the skinny on fats.

Steven E Nissen and Nina Tiecholz have an interesting article discussing the back story of the food pyramid scheme that seems to change based on a ring-around-the-posey strategy where grains, fats or carbs is left out.

Despite reams of clinical data on nutrition, our recommended daily doses are laughable for most nutrients. What we get through fortified foods is like trying to bail out a life boat with a thimble.

The food pyramid scheme is one more swing at raising consumer awareness about basic human nutritional health requirements.

It’s in our best interest to understand how nutrition science can impact the ‘owners manual’ for our own bodies.

 

Half Of Americans Sweet On Sodas

Sweeteners are hard to escape. It’s also hard to escape the health consequences of becoming overly reliant on a substance that apparently, not enough of us are yet aware is killing us slowly.

Half Of Americans Sweet On The Perils Of Sugar

According to the Centers for Disease Control and Prevention, recent statistics show half of Americans drink a soda or sugary beverage each day. We have gulped our way to a new milestone in that they include both adults and kids. So much for leading by example.

The American Diabetes Association’s Scientific Sessions suggest that drinking diet soda may be doing more harm than good.

Epidemiologists from the School of Medicine at the University of Texas Health Science Center San Antonio reported data showing that diet soft drink consumption is associated with increased waist circumference.

Related studies point to the illusion of the artificial

Diet soda users as a group experienced 70% greater increase in waist circumference compared with non-users. These results suggest aspartame exposure might potentially directly contribute to increased blood glucose levels. This in turn contributes to the associations observed between diet soda consumption and diabetes in humans.

With a majority of the population being obese, diabetic and increasingly unhealthy, it’s not so funny anymore to pitch junk to children so blatantly. First it was Joe Camel getting side lined, now Burger King says they are removing the King Mascot from the Throne.

Not to worry, researchers are working on an i–phone app to use with a tattoo that monitors glucose and sodium levels. Watch for more techno-bio feedback tools to learn appropriate healthy behaviors.

Researchers at Northeastern University are working on nano sensors tattooed under the skin. The sensors change shade, red for sodium and yellow for glucose. Not ready for humans just yet, but as they say, awareness is the first step to enlightenment. Measuring for it keeps us headed in the right direction. Hopefully we’ll get the message by the time it becomes a life and death matter,

Look at the labels of any packaged or processed food product. Sweeteners are hard to escape. It’s also hard to escape the health consequences of becoming overly reliant on a substance that apparently, not enough of us are yet aware of we all know is killing us slowly.Maybe the perils of sugar will become obvious to all of us. How about we stop subsidizing GMO corn processed high fructose corn syrup.

 

Your Fat Is Not Your Fault

Your Fat Is Not Your Fault!

In seven new approaches by seven experts reviewed, this is one common theme shared by the authors . All of them have been (or still are) in the trenches of individual coaching, and all have successfully guided hundreds and even thousands of clients to sustainable weight loss. And, all of them are promoting a healthy weight lifestyle.

Other common themes include poor or inappropriate diet, inflammation, malfunctioning digestion, and allergenic foods. Along with environmental toxins, these are named as the underlying causes of bloat and toxic fat deposits. However, the experts don’t always agree with each other.

Mindset, a customized approach, eating whole foods and “fit fats”, eliminating common food allergens, detoxification plans, and healing the gut trend throughout. Although to a person, the authors disdain the old eat-less-exercise-more approach, you’ll notice that you’ll be eating differently, often asked to fast, and be directed to follow an exercise routine.

All the programs are designed to keep you from feeling hungry, even those which utilize intermittent fasting. However, fasting is a learned mental discipline and can cause some discomfort on fasting days.

FYI: If you are over 40 and have trouble losing weight, you may need to supplement CoenzymeQ10. In one study, CoQ-deficient people took 100 mg per day. At the end of nine weeks, they had lost 30 lbs compared with only 13 lbs in the nondeficient group.

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