Could There Be A Reason Dietary Supplement Research Is Under Reported?

Doctors and other people sometimes say:

  • “I don’t see articles on vitamins in my professional journals.” 
  • “The research is simply not there.”
  • “Claims of nutrient efficacy and safety are not proven.”
  • “Many studies are published in little known and less respected journals.”
  • “I’ve never seen any studies supporting efficacy of nutrients.”

A  study from Wake Forest University illustrates the very obvious reasons for these uninformed opinions.

After reviewing eleven major medical journals including:

Not surprisingly, the journals with the most pharma ads published significantly fewer major articles about Dietary Supplements per issue than journals with the fewest pharma ads (P < 0.01).

 

Journals with the most pharma ads published no clinical trials or cohort studies about Dietary Supplements.

The percentage of major articles concluding that Dietary Supplements were unsafe was 4% in journals with fewest and 67% among those with the most pharma ads (P = 0.02).

The percentage of articles concluding that Dietary Supplements  were ineffective was 50% higher among journals with more than among those with fewer pharma ads (P = 0.4).

Conclusion:

These data are consistent with the hypothesis that increased pharmaceutical advertising is associated with publishing fewer articles about Dietary Supplements and publishing more articles with conclusions that Dietary Supplements are unsafe.

Additional research is needed to test alternative hypotheses for these findings in a larger sample of more diverse journals.

 

Thanks to Robert Greene for circulating the work of:
BMC Complement Altern Med. 2008; 8: 11.
Published online 2008 April 9. doi: 10.1186/1472-6882-8-11
.

PMCID: PMC2322947
Copyright © 2008 Kemper and Hood; licensee BioMed Central Ltd.

High Intake Of Folate May Be Protective Against Breast Cancer

A study published in the American Journal of Clinical Nutrition has found that very high folate intake may be protective against breast cancer. The trial included 35,023 women aged 50-76 years who participated in the Vitamins and Lifestyle (VITAL) cohort study. It was determined that between the years 2000 to 2006 a total of 743 women were diagnosed with invasive breast cancer. The researchers found that women who consumed 1,272 or more dietary folate equivalents (DFE)/day of total folate over an average 10-year period had a 22 percent decrease in breast cancer risk compared with women consuming 345 DFE/day or less. It was also discovered that the effect of very high folate intake was more pronounced when focusing on estrogen receptor (ER)-negative tumors alone, which is particularly important since ER-negative breast cancers generally have a poorer prognosis than their ER-positive counterparts. This research appears to indicate that high intakes of folate may actually be protective against breast cancer, especially ER-negative tumors.1

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Citrus Bergamot Lowers LDL

BRADENTON, Fla.—A new human clinical trial involving 82 dyslipidemic patients showed Bergamot (Citrus bergamia Risso) significantly reduced total cholesterol, low-density lipoprotein (LDL), triglycerides, blood glucose level and significantly increased high-density lipoprotein (HDL) cholesterol.

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